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GORD: fundoplication better short-term alternative to pills

A new Cochrane Systematic Review suggests that stomach wrap operations may be more effective than acid suppression tablets in the short- to medium-term treatment of gastro-oesophageal reflux disease.

18 Apr 2010

A new Cochrane Systematic Review suggests that stomach wrap operations may be more effective than acid suppression tablets in the short- to medium-term treatment of gastro-oesophageal reflux disease.

The authors, led by Dr Samantha Wileman, of the University of Aberdeen, reviewed data from four trials involving 1,232 subjects. Their conclusions relate to findings from follow-up to one year after treatment.

They report finding that fundoplication procedures performed by keyhole surgery were more effective at reducing GORD symptoms over this period.

But Dr Wileman warned that there were few data available to indicate benefit over longer periods, pointing out that, because earlier research (ie, before keyhole surgery was developed for GORD) had suggested that the benefits of surgery for the condition were not sustained over time, “we need to know more about the clinical and cost implications of long-term medication versus surgery”.


Published: 18 Apr 2010