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Cardiac study: twins needed

St Vincent’s in Sydney and the Victor Chang Cardiac Research Unit are looking for twins to take part in a study into the relationship between genes and heart electrical activity. The twins can come in all varieties: identical, non-identical, same sex, different sex. But they have to be aged between 18 and 35, be non-smokers, have no major health problems and taking no regular medication. They also need to be happy about wearing an ECG (Holter) monitor for 24 hours.

15 Oct 2012

St Vincent’s in Sydney and the Victor Chang Cardiac Research Unit are looking for twins to take part in a study into the relationship between genes and heart electrical activity.

The twins can come in all varieties: identical, non-identical, same sex, different sex. But they have to be aged between 18 and 35, be non-smokers, have no major health problems and taking no regular medication. They also need to be happy about wearing an ECG (Holter) monitor for 24 hours.

The reason for the study is to assess the relationship between heart tracing appearance on a Holter monitor and differences in DNA between different people.

In normal, healthy people, while some variations in ECG characteristics (thought to be caused by differences in how an individual’s DNA is used by the body) may protect against abnormal heart beat, others may increase the risk. With the Holter monitoring, the twins can help discover how the gene-heart activity interaction works because they share genetic code - 100 per cent in the case of identical twins, 50 per cent in non-identical twins.

Contacts for more information are principal investigator Professor Jamie Vandenberg at j.vanderberg@victorchang.edu.au or research assistant Dr Emily Hodkinson at e.hodkinson@victorchangedu.au or (02) 9295 8600.

DN


Published: 15 Oct 2012